{"studyId":"msk_spectrum_tme_2022","cancerTypeId":"ovary","name":"Ovarian Cancer - MSK SPECTRUM (MSK, Nature 2022)","description":"Multi-region, multi-modal profiling of 42 untreated high-grade serous ovarian cancer (HGSOC) tumor/normal pairs. This study reports an integrative analysis of mutational processes and their impact on the tumor microenvironment using single-cell RNA sequencing, whole-genome sequencing, targeted sequencing (MSK-IMPACT), digital histopathology and multiplexed immunofluorescence. The study is part of a prospective research program to understand the spatio-temporal determinants of HGSOC evolution, treatment and response (MSK SPECTRUM: Memorial Sloan Kettering - SPatio-temporal Evolution in Cancer TRaced Using Multimodalities).","publicStudy":true,"pmid":"36517593","citation":"Vázquez-García, Uhlitz et al. Nature 2022","groups":"PUBLIC","status":1,"importDate":"2026-01-08 17:24:46","allSampleCount":82,"sequencedSampleCount":82,"cnaSampleCount":82,"mrnaRnaSeqSampleCount":0,"mrnaRnaSeqV2SampleCount":0,"mrnaMicroarraySampleCount":0,"miRnaSampleCount":0,"methylationHm27SampleCount":0,"rppaSampleCount":0,"massSpectrometrySampleCount":0,"completeSampleCount":0,"referenceGenome":"hg19","treatmentCount":0,"structuralVariantCount":20,"cancerType":{"id":"ovary","name":"Ovary/Fallopian Tube","dedicatedColor":"LightBlue","shortName":"OVARY","parent":"tissue"},"readPermission":true,"resourceCounts":[{"resourceId":"HE","displayName":"H&E Slide","description":"H&E Slide","resourceType":"SAMPLE","priority":"1","openByDefault":true,"cancerStudyIdentifier":"msk_spectrum_tme_2022","sampleCount":37,"patientCount":33},{"resourceId":"CHROMOSCOPE","displayName":"Chromoscope","description":"Link to Chromoscope","resourceType":"SAMPLE","priority":"2","openByDefault":true,"cancerStudyIdentifier":"msk_spectrum_tme_2022","sampleCount":39,"patientCount":39},{"resourceId":"MXIF","displayName":"MxIF Image","description":"MxIF Images","resourceType":"PATIENT","priority":"1","openByDefault":true,"cancerStudyIdentifier":"msk_spectrum_tme_2022","sampleCount":8,"patientCount":4}]}